Digital Image Processing Using MATLAB offers a balanced treatment of image processing fundamentals and the software principles used in their implementation. The book integrates material from the 4th edition of Digital Image Processing by Gonzalez and Woods, the leading textbook in the field, and Image Processing Toolbox. Image Processing Toolbox provides a stable, well-supported software environment for addressing a broad range of applications in digital image processing. A unique feature of the book is its emphasis on showing how to enhance these tools by developing new code. This is important in image processing, a field that generally requires extensive experimental work in order to arrive at suitable application solutions.
digital image processing by jayaraman ebook 11
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Abstract: Simple SummaryWe review advances in the properties of calcium sensors, microscopy, and data analysis that have brought about the ability to image large contiguous regions of the mouse brain, often termed wide-field or mesoscale imaging. We summarize representative wide-field imaging studies spanning several neuroscience subfields, providing an overview of insights gained into brain function. Finally, we present new developments in wide-field imaging that allow for more comprehensive investigation of activity across the brain. AbstractA central tenet of neuroscience is that sensory, motor, and cognitive behaviors are generated by the communications and interactions among neurons, distributed within and across anatomically and functionally distinct brain regions. Therefore, to decipher how the brain plans, learns, and executes behaviors requires characterizing neuronal activity at multiple spatial and temporal scales. This includes simultaneously recording neuronal dynamics at the mesoscale level to understand the interactions among brain regions during different behavioral and brain states. Wide-field Ca2+ imaging, which uses single photon excitation and improved genetically encoded Ca2+ indicators, allows for simultaneous recordings of large brain areas and is proving to be a powerful tool to study neuronal activity at the mesoscopic scale in behaving animals. This review details the techniques used for wide-field Ca2+ imaging and the various approaches employed for the analyses of the rich neuronal-behavioral data sets obtained. Also discussed is how wide-field Ca2+ imaging is providing novel insights into both normal and altered neural processing in disease. Finally, we examine the limitations of the approach and new developments in wide-field Ca2+ imaging that are bringing new capabilities to this important technique for investigating large-scale neuronal dynamics.Keywords: mesoscopic imaging; calcium imaging; neuronal dynamics; functional connectivity; spatial independent component analysis
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